ChloroquineV1, Main, Exploration, bibRecord, 002A74

Treatment of cutaneous and pulmonary sarcoidosis with thalidomide

Identifieur interne : 002A74 ( Main/Exploration ); précédent : 002A73; suivant : 002A75

Treatment of cutaneous and pulmonary sarcoidosis with thalidomide

Auteurs : Marta Carlesimo [Italie] ; Sandra Giustini [Italie] ; Alfredo Rossi [Italie] ; Paola Bonaccorsi [Italie] ; Stefano Calvieri [Italie]

Source :

Journal of the American Academy of Dermatology [ 0190-9622 ] ; 1995.

RBID : ISTEX:7205D59B5BC04B12381F5D96C2B9A01A1C3502BD

English descriptors

Teeft :
- Acad, Acad dermatol, Adverse reactions, Alternate days, American academy, Angiotensin, Arch dermatol, Bronchoalveolar, Bronchoalveolar lavage, Carlesimo, Clinical course, Corticosteroid, Cutaneous, Dermatol, Dermatol venereol, Dermatology, Dermatology volume, Erythrocyte sedimentation rate, Lepra, Lepra reaction, Macrophage, Macrophage function, Pulmonary sarcoidosis, Sarcoidosis, Sarcoma, Serum angiotensin, Serum enzyme activity, Stefano calvieri, Systemic corticosteroid therapy, Systemic corticosteroids, Systemic sarcoidosis, Thalidomide, Thalidomide therapy, Therapeutic agents, Venereol, Violaceous plaque.

Abstract

Abstract: Many therapeutic agents have been proposed for treatment of steroid-resistant sarcoidosis. Because administration of low doses of thalidomide has been successful in treating other inflammatory diseases, it was used in a patient with systemic sarcoidosis who was unresponsive to corticosteroids and in a patient with pulmonary sarcoidosis, in whom Kaposi's sarcoma developed after a course of corticosteroid therapy. Thalidomide, 200 mg/day for 2 weeks followed by 100 mg/day for 11 weeks, was given. This treatment was effective in both patients. No adverse reactions were observed. Thalidomide, 100 mg on alternate days, is still being administered. No relapse has occurred. Thalidomide, particularly because of its inhibition of the macrophage function, may be a useful alternative therapy in steroid-resistant cases. In addition, the correlation between the angiotensin-converting enzyme level and the clinical improvement observed in our patients suggests a direct parallel between angiotensin-converting enzyme and the activity of the granulomatous process.

Url:

https://api.istex.fr/ark:/67375/6H6-DJ620N2Z-R/fulltext.pdf

DOI: 10.1016/0190-9622(95)91549-4

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: 001925
to stream Istex, to step Curation: 001925
to stream Istex, to step Checkpoint: 001860
to stream Main, to step Merge: 002B29
to stream Main, to step Curation: 002A74

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Treatment of cutaneous and pulmonary sarcoidosis with thalidomide</title>
<author><name sortKey="Carlesimo, Marta" sort="Carlesimo, Marta" uniqKey="Carlesimo M" first="Marta" last="Carlesimo">Marta Carlesimo</name>
</author>
<author><name sortKey="Giustini, Sandra" sort="Giustini, Sandra" uniqKey="Giustini S" first="Sandra" last="Giustini">Sandra Giustini</name>
</author>
<author><name sortKey="Rossi, Alfredo" sort="Rossi, Alfredo" uniqKey="Rossi A" first="Alfredo" last="Rossi">Alfredo Rossi</name>
</author>
<author><name sortKey="Bonaccorsi, Paola" sort="Bonaccorsi, Paola" uniqKey="Bonaccorsi P" first="Paola" last="Bonaccorsi">Paola Bonaccorsi</name>
</author>
<author><name sortKey="Calvieri, Stefano" sort="Calvieri, Stefano" uniqKey="Calvieri S" first="Stefano" last="Calvieri">Stefano Calvieri</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:7205D59B5BC04B12381F5D96C2B9A01A1C3502BD</idno>
<date when="1995" year="1995">1995</date>
<idno type="doi">10.1016/0190-9622(95)91549-4</idno>
<idno type="url">https://api.istex.fr/ark:/67375/6H6-DJ620N2Z-R/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001925</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001925</idno>
<idno type="wicri:Area/Istex/Curation">001925</idno>
<idno type="wicri:Area/Istex/Checkpoint">001860</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001860</idno>
<idno type="wicri:doubleKey">0190-9622:1995:Carlesimo M:treatment:of:cutaneous</idno>
<idno type="wicri:Area/Main/Merge">002B29</idno>
<idno type="wicri:Area/Main/Curation">002A74</idno>
<idno type="wicri:Area/Main/Exploration">002A74</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a">Treatment of cutaneous and pulmonary sarcoidosis with thalidomide</title>
<author><name sortKey="Carlesimo, Marta" sort="Carlesimo, Marta" uniqKey="Carlesimo M" first="Marta" last="Carlesimo">Marta Carlesimo</name>
<affiliation wicri:level="3"><country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Dermatology, University of Rome “La Sapienza”, Rome</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Giustini, Sandra" sort="Giustini, Sandra" uniqKey="Giustini S" first="Sandra" last="Giustini">Sandra Giustini</name>
<affiliation wicri:level="3"><country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Dermatology, University of Rome “La Sapienza”, Rome</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rossi, Alfredo" sort="Rossi, Alfredo" uniqKey="Rossi A" first="Alfredo" last="Rossi">Alfredo Rossi</name>
<affiliation wicri:level="3"><country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Dermatology, University of Rome “La Sapienza”, Rome</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bonaccorsi, Paola" sort="Bonaccorsi, Paola" uniqKey="Bonaccorsi P" first="Paola" last="Bonaccorsi">Paola Bonaccorsi</name>
<affiliation wicri:level="3"><country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Dermatology, University of Rome “La Sapienza”, Rome</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Calvieri, Stefano" sort="Calvieri, Stefano" uniqKey="Calvieri S" first="Stefano" last="Calvieri">Stefano Calvieri</name>
<affiliation wicri:level="3"><country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Dermatology, University of Rome “La Sapienza”, Rome</wicri:regionArea>
<placeName><settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Journal of the American Academy of Dermatology</title>
<title level="j" type="abbrev">YMJD</title>
<idno type="ISSN">0190-9622</idno>
<imprint><publisher>ELSEVIER</publisher>
<date type="published" when="1995">1995</date>
<biblScope unit="volume">32</biblScope>
<biblScope unit="issue">5</biblScope>
<biblScope unit="supplement">P2</biblScope>
<biblScope unit="page" from="866">866</biblScope>
<biblScope unit="page" to="869">869</biblScope>
</imprint>
<idno type="ISSN">0190-9622</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0190-9622</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acad</term>
<term>Acad dermatol</term>
<term>Adverse reactions</term>
<term>Alternate days</term>
<term>American academy</term>
<term>Angiotensin</term>
<term>Arch dermatol</term>
<term>Bronchoalveolar</term>
<term>Bronchoalveolar lavage</term>
<term>Carlesimo</term>
<term>Clinical course</term>
<term>Corticosteroid</term>
<term>Cutaneous</term>
<term>Dermatol</term>
<term>Dermatol venereol</term>
<term>Dermatology</term>
<term>Dermatology volume</term>
<term>Erythrocyte sedimentation rate</term>
<term>Lepra</term>
<term>Lepra reaction</term>
<term>Macrophage</term>
<term>Macrophage function</term>
<term>Pulmonary sarcoidosis</term>
<term>Sarcoidosis</term>
<term>Sarcoma</term>
<term>Serum angiotensin</term>
<term>Serum enzyme activity</term>
<term>Stefano calvieri</term>
<term>Systemic corticosteroid therapy</term>
<term>Systemic corticosteroids</term>
<term>Systemic sarcoidosis</term>
<term>Thalidomide</term>
<term>Thalidomide therapy</term>
<term>Therapeutic agents</term>
<term>Venereol</term>
<term>Violaceous plaque</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Abstract: Many therapeutic agents have been proposed for treatment of steroid-resistant sarcoidosis. Because administration of low doses of thalidomide has been successful in treating other inflammatory diseases, it was used in a patient with systemic sarcoidosis who was unresponsive to corticosteroids and in a patient with pulmonary sarcoidosis, in whom Kaposi's sarcoma developed after a course of corticosteroid therapy. Thalidomide, 200 mg/day for 2 weeks followed by 100 mg/day for 11 weeks, was given. This treatment was effective in both patients. No adverse reactions were observed. Thalidomide, 100 mg on alternate days, is still being administered. No relapse has occurred. Thalidomide, particularly because of its inhibition of the macrophage function, may be a useful alternative therapy in steroid-resistant cases. In addition, the correlation between the angiotensin-converting enzyme level and the clinical improvement observed in our patients suggests a direct parallel between angiotensin-converting enzyme and the activity of the granulomatous process.</div>
</front>
</TEI>
<affiliations><list><country><li>Italie</li>
</country>
<region><li>Latium</li>
</region>
<settlement><li>Rome</li>
</settlement>
</list>
<tree><country name="Italie"><region name="Latium"><name sortKey="Carlesimo, Marta" sort="Carlesimo, Marta" uniqKey="Carlesimo M" first="Marta" last="Carlesimo">Marta Carlesimo</name>
</region>
<name sortKey="Bonaccorsi, Paola" sort="Bonaccorsi, Paola" uniqKey="Bonaccorsi P" first="Paola" last="Bonaccorsi">Paola Bonaccorsi</name>
<name sortKey="Calvieri, Stefano" sort="Calvieri, Stefano" uniqKey="Calvieri S" first="Stefano" last="Calvieri">Stefano Calvieri</name>
<name sortKey="Giustini, Sandra" sort="Giustini, Sandra" uniqKey="Giustini S" first="Sandra" last="Giustini">Sandra Giustini</name>
<name sortKey="Rossi, Alfredo" sort="Rossi, Alfredo" uniqKey="Rossi A" first="Alfredo" last="Rossi">Alfredo Rossi</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002A74 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002A74 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:7205D59B5BC04B12381F5D96C2B9A01A1C3502BD
   |texte=   Treatment of cutaneous and pulmonary sarcoidosis with thalidomide
}}

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

	Serveur d'exploration Chloroquine
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Chloroquine

Treatment of cutaneous and pulmonary sarcoidosis with thalidomide

Treatment of cutaneous and pulmonary sarcoidosis with thalidomide

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri